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Magic™ Antibody Discovery - Human IL-37 / IL-1F7b (46-218) Membrane Protein, Partial, His- tag (CAT#: MP0863F)

Datasheet
This membrane protein is Human IL-37 / IL-1F7b (98-330). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IL-37 / IL-1F7b
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 20.3 kDa. The protein migrates as 20.3 kDa under reducing (R) condition (SDS-PAGE).
  • Sequence
  • AA Val 46 - Asp 218 (Accession # AAH20637.1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • E.coli
  • Tag
  • His tag at the N-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • IL-37 / IL-1F7b
  • Full Name
  • interleukin 37
  • Introduction
  • The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.
  • Alternative Names
  • FIL1; FIL1Z; IL-1H; IL-23; IL-37; IL1F7; IL1H4; IL-1F7; IL-1H4; IL1RP1; IL-1RP1; FIL1(ZETA); interleukin-37; FIL1 zeta; IL-1 zeta; IL-1F7b (IL-1H4, IL-1H, IL-1RP1); IL-1X protein; IL1F7 (canonical product IL-1F7b); interleukin 1 family member 7; interleukin 1, zeta; interleukin-1 homolog 4; interleukin-1 superfamily z; interleukin-1-related protein; interleukin-23

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