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Magic™ Antibody Discovery - Human Integrin alpha 9 beta 1 (ITGA9&ITGB1) (27-239) Membrane Protein, Partial, -His Tag & Tag free (CAT#: MP0855F)

Datasheet
This membrane protein is Human Integrin alpha 9 beta 1 (ITGA9&ITGB1) (24-540). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Integrin alpha 9 beta 1 (ITGA9&ITGB1)
  • Protein Length
  • ECD
  • Molecular Weight
  • Calculated MW of 111.1 kDa (ITGA9) and 82.7 kDa (ITGB1).
  • Sequence
  • AA Tyr 30 - Trp 981 (ITGA9) & Gln 21 - Asp 728 (ITGB1) (Accession # Q13797-1 (ITGA9) & P05556-1 (ITGB1)).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • ITGA9 is fused with an acidic tail at the C-terminus and followed by a His tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus.
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

Target

  • Target Protein
  • Integrin alpha 9 beta 1 (ITGA9&ITGB1)
  • Full Name
  • integrin subunit alpha 9&integrin subunit beta 1
  • Introduction
  • This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers.&Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.
  • Alternative Names
  • Integrin alpha 9 beta 1, ITGA9 & ITGB1

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