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Magic™ Antibody Discovery - Human LAG-3 / CD223 (23-450) Membrane Protein, Partial, -mIgG2a Fc tag (CAT#: MP0558F)

Datasheet
This membrane protein is Human LAG-3 / CD223 (23-450). It has been tested in SDS-PAGE, ELISA, FACS. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • LAG-3 / CD223
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 73.3 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Leu 23 - Leu 450 (Accession # P18627-1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA, FACS
  • Expression Systems
  • HEK293
  • Tag
  • Mouse IgG2a Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • LAG-3 / CD223
  • Full Name
  • lymphocyte activating 3
  • Introduction
  • Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4.
  • Alternative Names
  • CD223; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3

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