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Magic™ Antibody Discovery - Human Niemann-Pick Type C2 / NPC2 (20-151) Membrane Protein, Partial, -His tag, [PE] (CAT#: MP0682F)

Datasheet
This membrane protein is Human Niemann-Pick Type C2 / NPC2 (20-151). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Niemann-Pick Type C2 / NPC2
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 16.5 kDa. The protein migrates as 21 kDa and 24-27 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Glu 20 - Leu 151 (Accession # P61916-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Conjugation
  • PE
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Niemann-Pick Type C2 / NPC2
  • Full Name
  • NPC intracellular cholesterol transporter 2
  • Introduction
  • This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy.
  • Alternative Names
  • HE1; EDDM1; NPC intracellular cholesterol transporter 2; Niemann-Pick disease type C2 protein; epididymal protein 1; epididymis secretory sperm binding protein; human epididymis-specific protein 1; tissue-specific secretory protein

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