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Magic™ Antibody Discovery - Human PTPRD (21-1265) Membrane Protein, Partial, -His tag (CAT#: MP0801F)

Datasheet
This membrane protein is Human PTPRD (82-190). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PTPRD
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 140.0 kDa. The protein migrates as 19 kDa and 120-130 kDa under reducing (R) condition (SDS-PAGE).
  • Sequence
  • AA Glu 21 - Glu 1265 (Accession # P23468-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >90% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • PTPRD
  • Full Name
  • protein tyrosine phosphatase receptor type D
  • Introduction
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5.
  • Alternative Names
  • HPTP; PTPD; HPTPD; HPTPDELTA; RPTPDELTA; R-PTP-delta; receptor-type tyrosine-protein phosphatase delta; protein tyrosine phosphatase, receptor type, delta polypeptide; rceptor-type tyrosine-protein phosphatase delta

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