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Magic™ Antibody Discovery - Human / Rhesus macaque CD40 Ligand / TNFSF5 (113-261) Membrane Protein, Partial, mIgG2a Fc- tag, low endotoxin (CAT#: MP1270F)

Datasheet
This membrane protein is Human / Rhesus macaque CD40 Ligand / TNFSF5 (113-261). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human / Rhesus macaque
  • Target Protein
  • CD40 Ligand / TNFSF5
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 43.1 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Met 113 - Leu 261 (Accession # P29965-1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA
  • Expression Systems
  • HEK293
  • Tag
  • Mouse IgG2a Fc tag at the N-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <0.1 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • CD40 Ligand / TNFSF5
  • Full Name
  • CD40 ligand
  • Introduction
  • The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
  • Alternative Names
  • IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L; CD40 ligand; CD40 antigen ligand; CD40-L; T-B cell-activating molecule; T-cell antigen Gp39; TNF-related activation protein; tumor necrosis factor (ligand) superfamily member 5

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