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Magic™ Antibody Discovery - Human TRAIL R1 / DR4 / TNFRSF10A (24-239) Membrane Protein, Partial, -His tag (CAT#: MP0499F)

Datasheet
This membrane protein is Human TRAIL R1 / DR4 / TNFRSF10A (24-239). It has been tested in SDS-PAGE, ELISA, BLI. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TRAIL R1 / DR4 / TNFRSF10A
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 24.8 kDa. The protein migrates as 20-23 kDa under reducing (R) condition (SDS-PAGE).
  • Sequence
  • AA Ala 24 - Asn 239 (Accession # NP_003835).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA, BLI
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >90% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • TRAIL R1 / DR4 / TNFRSF10A
  • Full Name
  • TNF receptor superfamily member 10a
  • Introduction
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.
  • Alternative Names
  • DR4; APO2; CD261; TRAILR1; TRAILR-1; tumor necrosis factor receptor superfamily member 10A; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1; cytotoxic TRAIL receptor; death receptor 4; tumor necrosis factor receptor superfamily member 10a variant 2; tumor necrosis factor receptor superfamily, member 10a

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