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Magic™ Antibody Discovery - Mouse GUCY2C / Guanylyl cyclase C (20-433) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP0133F)

Datasheet
This membrane protein is Mouse GUCY2C / Guanylyl cyclase C (20-433). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Mouse
  • Target Protein
  • GUCY2C / Guanylyl cyclase C
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 73.5 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation
  • Sequence
  • AA Val 20 - Met 433 (Accession # Q3UWA6-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • GUCY2C / Guanylyl cyclase C
  • Full Name
  • guanylate cyclase 2c
  • Introduction
  • This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive).
  • Alternative Names
  • Gcc; GC-C; AI893437; heat-stable enterotoxin receptor; STA receptor; guanylyl cyclase C; intestinal guanylate cyclase

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