Close
Close

Magic™ Membrane Protein Bacterial BmrA (Multidrug resistance ABC transporter ATP-binding protein/permease BmrA) (CAT#: MP0040F)

Datasheet
BmrA Transporters aid in the exploration, improvement, validation of novel molecules and therapeutic antibodies. Our BmrA transporters are excellent for therapeutic indications such as bacterial resistance to antibiotics.

Product Specifications

  • Host Species
  • Bacterial
  • Target Protein
  • BmrA
  • Protein Length
  • Full-length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 64.5 kDa
  • TMD
  • 6
  • Sequence
  • MSSSHHHHHHMPTKKQKSKSKLKPFFALVRRTNPSYGKLAFALALSVVTTLVSLLIPLLTKQLVDGFS
    MSNLSGTQIGLIALVFFVQAGLSAYATYALNYNGQKIISGLRELLWKKLIKLPVSYFDTNASGETVSRV
    TNDTMVVKELITTHISGFITGIISVIGSLTILFIMNWKLTLLVLVVVPLAALILVPIGRKMFSISRETQDE
    TARFTGLLNQILPEIRLVKASNAEDVEYGRGKMGISSLFKLGVREAKVQSLVGPLISLVLMAALVAVIG
    YGGMQVSSGELTAGALVAFILYLFQIIMPMGQITTFFTQLQKSIGATERMIEILAEEEEDTVTGKQIEN
    AHLPIQLDRVSFGYKPDQLILKEVSAVIEAGKVTAIVGPSGGGKTTLFKLLERFYSPTAGTIRLGDEPV
    DTYSLESWREHIGYVSQESPLMSGTIRENICYGLERDVTDAEIEKAAEMAYALNFIKELPNQFDTEVG
    ERGIMLSGGQRQRIAIARALLRNPSILMLDEATSSLDSQSEKSVQQALEVLMEGRTTIVIAHRLSTVV
    DADQLLFVEKGEITGRGTHHELMASHGLYRDFAEQQLKMNADLENKAG

Product Description

  • Activity
  • Confirmed by ATPase activity assay
  • Expression Systems
  • E.coli
  • Tag
  • His-tag (N-terminal)
  • Purification
  • Immobilized Metal Affinity Chromatography
  • Purity
  • >90%
  • Buffer
  • 50mM Tris-Cl pH 8.0, 100 mM NaCl, 0.01% DDM, 10%glycerol

Target

  • Target Protein
  • BmrA
  • Full Name
  • Multidrug resistance ABC transporter ATP-binding protein/permease BmrA
  • Introduction
  • An efflux transporter able to transport Hoechst 33342, ethidium bromide, doxorubicin and a number of other drugs in vitro into inside out vesicles. The endogenous substrate is unknown. It has been suggested that NBD dimerization induced by ATP-binding causes a large conformational change responsible for substrate translocation. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
  • Alternative Names
  • bmrA

Customer reviews and Q&As    

Related Products
Online Inquiry
CONTACT US
USA:
Europe:
Germany:
Call us at:
USA:
UK:
Germany:
Fax:
Email:
Our customer service representatives are available 24 hours a day, 7 days a week. Contact Us
© 2024 Creative Biolabs. | Contact Us