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Magic™ Membrane Protein Human ABCB8 (ATP binding cassette subfamily B member 8) Full Length (CAT#: MPC1879K) Made to Order

This product is a 79.9 kDa Human ABCB8 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ABCB8
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 79.9 kDa
  • TMD
  • 3
  • Sequence
  • MLVHLFRVGIRGGPFPGRLLPPLRFQTFSAVRNTWRNGKTGQLHKAEGEY
    SDGYRSSSLLRAVAHLRSQLWAHLPRAPLAPRWSPSAWCWVGGALLGPMV
    LSKHPHLCLVALCEAEEAPPASSTPHVVGSRFNWKLFWQFLHPHLLVLGV
    AVVLALGAALVNVQIPLLLGQLVEVVAKYTRDHVGSFMTESQNLSTHLLI
    LYGVQGLLTFGYLVLLSHVGERMAVDMRRALFSSLLRQDITFFDANKTGQ
    LVSRLTTDVQEFKSSFKLVISQGLRSCTQVAGCLVSLSMLSTRLTLLLMV
    ATPALMGVGTLMGSGLRKLSRQCQEQIARAMGVADEALGNVRTVRAFAME
    QREEERYGAELEACRCRAEELGRGIALFQGLSNIAFNCMVLGTLFIGGSL
    VAGQQLTGGDLMSFLVASQTVQRSMANLSVLFGQVVRGLSAGARVFEYMA
    LNPCIPLSGGCCVPKEQLRGSVTFQNVCFSYPCRPGFEVLKDFTLTLPPG
    KIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQV
    VGFISQEPVLFGTTIMENIRFGKLEASDEEVYTAAREANAHEFITSFPEG
    YNTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVV
    QEALDRASAGRTVLVIAHRLSTVRGAHCIVVMADGRVWEAGTHEELLKKG
    GLYAELIRRQALDAPRTAAPPPKKPEGPRSHQHKS

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ABCB8
  • Full Name
  • ATP binding cassette subfamily B member 8
  • Introduction
  • This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • ABCB8; MABC1; M-ABC1; MITOSUR; EST328128; mitochondrial potassium channel ATP-binding subunit; ATP-binding cassette sub-family B member 8, mitochondrial; ATP-binding cassette, sub-family B (MDR/TAP), member 8; mitochondrial ABC protein; mitochondrial ATP-binding cassette 1; mitochondrial sulfonylurea-receptor; ATP binding cassette subfamily B member 8

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