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Magic™ Membrane Protein Human ADCY6 (Adenylate cyclase 6) Full Length (CAT#: MPC1982K) Made to Order

Datasheet
This product is a 130.6 kDa Human ADCY6 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ADCY6
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 130.6 kDa
  • TMD
  • 12
  • Sequence
  • MSWFSGLLVPKVDERKTAWGERNGQKRSRRRGTRAGGFCTPRYMSCLRDA
    EPPSPTPAGPPRCPWQDDAFIRRGGPGKGKELGLRAVALGFEDTEVTTTA
    GGTAEVAPDAVPRSGRSCWRRLVQVFQSKQFRSAKLERLYQRYFFQMNQS
    SLTLLMAVLVLLTAVLLAFHAAPARPQPAYVALLACAAALFVGLMVVCNR
    HSFRQDSMWVVSYVVLGILAAVQVGGALAADPRSPSAGLWCPVFFVYIAY
    TLLPIRMRAAVLSGLGLSTLHLILAWQLNRGDAFLWKQLGANVLLFLCTN
    VIGICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHV
    AMEMKEDINTKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQEL
    VMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEM
    GVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVT
    LANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNAYLKEQHIETF
    LILGASQKRKEEKAMLAKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFR
    QMGIDDSSKDNRGTQDALNPEDEVDEFLSRAIDARSIDQLRKDHVRRFLL
    TFQREDLEKKYSRKVDPRFGAYVACALLVFCFICFIQLLIFPHSTLMLGI
    YASIFLLLLITVLICAVYSCGSLFPKALQRLSRSIVRSRAHSTAVGIFSV
    LLVFTSAIANMFTCNHTPIRSCAARMLNLTPADITACHLQQLNYSLGLDA
    PLCEGTMPTCSFPEYFIGNMLLSLLASSVFLHISSIGKLAMIFVLGLIYL
    VLLLLGPPATIFDNYDLLLGVHGLASSNETFDGLDCPAAGRVALKYMTPV
    ILLVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHN
    ILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNE
    GVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNASTYDQ
    VGRSHITALADYAMRLMEQMKHINEHSFNNFQMKIGLNMGPVVAGVIGAR
    KPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQLECRGVVK
    VKGKGEMTTYFLNGGPSS

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ADCY6
  • Full Name
  • Adenylate cyclase 6
  • Introduction
  • This gene encodes a member of the adenylyl cyclase family of proteins, which are required for the synthesis of cyclic AMP. All members of this family have an intracellular N-terminus, a tandem repeat of six transmembrane domains separated by a cytoplasmic loop, and a C-terminal cytoplasmic domain. The two cytoplasmic regions bind ATP and form the catalytic core of the protein. Adenylyl cyclases are important effectors of transmembrane signaling pathways and are regulated by the activity of G protein coupled receptor signaling. This protein belongs to a small subclass of adenylyl cyclase proteins that are functionally related and are inhibited by protein kinase A, calcium ions and nitric oxide. A mutation in this gene is associated with arthrogryposis multiplex congenita.
  • Alternative Names
  • ADCY6; AC6; LCCS8; adenylate cyclase type 6; ATP pyrophosphate-lyase 6; adenylate cyclase type VI; ca(2+)-inhibitable adenylyl cyclase; Adenylate cyclase 6

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