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Magic™ Membrane Protein Human ASIC2 (Acid sensing ion channel subunit 2) Full Length (CAT#: MPC0402K) Made to Order

Datasheet
This product is a 57.7 kDa Human ASIC2 membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ASIC2
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 57.7 kDa
  • TMD
  • 2
  • Sequence
  • MDLKESPSEGSLQPSSIQIFANTSTLHGIRHIFVYGPLTIRRVLWAVAFV
    GSLGLLLVESSERVSYYFSYQHVTKVDEVVAQSLVFPAVTLCNLNGFRFS
    RLTTNDLYHAGELLALLDVNLQIPDPHLADPSVLEALRQKANFKHYKPKQ
    FSMLEFLHRVGHDLKDMMLYCKFKGQECGHQDFTTVFTKYGKCYMFNSGE
    DGKPLLTTVKGGTGNGLEIMLDIQQDEYLPIWGETEETTFEAGVKVQIHS
    QSEPPFIQELGFGVAPGFQTFVATQEQRLTYLPPPWGECRSSEMGLDFFP
    VYSITACRIDCETRYIVENCNCRMVHMPGDAPFCTPEQHKECAEPALGLL
    AEKDSNYCLCRTPCNLTRYNKELSMVKIPSKTSAKYLEKKFNKSEKYISE
    NILVLDIFFEALNYETIEQKKAYEVAALLGDIGGQMGLFIGASILTILEL
    FDYIYELIKEKLLDLLGKEEDEGSHDENVSTCDTMPNHSETISHTVNVPL
    QTTLGTLEEIAC

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ASIC2
  • Full Name
  • Acid sensing ion channel subunit 2
  • Introduction
  • This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified.
  • Alternative Names
  • ACCN; BNC1; MDEG; ACCN1; BNaC1; ASIC2a; hBNaC1; acid-sensing ion channel 2; acid sensing (proton gated) ion channel 2; amiloride-sensitive cation channel 1, neuronal; brain sodium channel 1; mammalian degenerin homolog; neuronal amiloride-sensitive cation channel 1; ASIC2; Acid sensing ion channel subunit 2
  • Gene ID
  • 40

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