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Magic™ Membrane Protein Human ATP8B1 (ATPase phospholipid transporting 8B1) Full Length (CAT#: MPC0408K) Made to Order

This product is a 143.6 kDa Human ATP8B1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ATP8B1
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 143.6 kDa
  • TMD
  • 10
  • Sequence
  • MSTERDSETTFDEDSQPNDEVVPYSDDETEDELDDQGSAVEPEQNRVNRE
    AEENREPFRKECTWQVKANDRKYHEQPHFMNTKFLCIKESKYANNAIKTY
    KYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLLV
    VLGVTAIKDLVDDVARHKMDKEINNRTCEVIKDGRFKVAKWKEIQVGDVI
    RLKKNDFVPADILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYL
    QREDTLATFDGFIECEEPNNRLDKFTGTLFWRNTSFPLDADKILLRGCVI
    RNTDFCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFVVLIL
    LSAGLAIGHAYWEAQVGNSSWYLYDGEDDTPSYRGFLIFWGYIIVLNTMV
    PISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTLNEQLGQIHY
    IFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQHNHNKIEQVDFSWNTY
    ADGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVDRTDGQLNYQA
    ASPDEGALVNAARNFGFAFLARTQNTITISELGTERTYNVLAILDFNSDR
    KRMSIIVRTPEGNIKLYCKGADTVIYERLHRMNPTKQETQDALDIFANET
    LRTLCLCYKEIEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLIL
    LGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFACELLT
    EDTTICYGEDINSLLHARMENQRNRGGVYAKFAPPVQESFFPPGGNRALI
    ITGSWLNEILLEKKTKRNKILKLKFPRTEEERRMRTQSKRRLEAKKEQRQ
    KNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNM
    IKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKF
    LRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLM
    GLLDQDVSDKLSLRFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFI
    PLGAYLQTVGQDGEAPSDYQSFAVTIASALVITVNFQIGLDTSYWTFVNA
    FSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTASNALRQPYIWLTII
    LAVAVCLLPVVAIRFLSMTIWPSESDKIQKHRKRLKAEEQWQRRQQVFRR
    GVSTRRSAYAFSHQRGYADLISSGRSIRKKRSPLDAIVADGTAEYRRTGD
    S

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ATP8B1
  • Full Name
  • ATPase phospholipid transporting 8B1
  • Introduction
  • This gene encodes a member of the P-type cation transport ATPase family, which belongs to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. Mutations in this gene may result in progressive familial intrahepatic cholestasis type 1 and in benign recurrent intrahepatic cholestasis.
  • Alternative Names
  • BRIC; FIC1; ICP1; PFIC; ATPIC; PFIC1; phospholipid-transporting ATPase IC; ATPase, aminophospholipid transporter, class I, type 8B, member 1; ATPase, class I, type 8B, member 1; E1-E2 ATPase; P4-ATPase flippase complex alpha subunit ATP8B1; familial intrahepatic cholestasis type 1; probable phospholipid-transporting ATPase IC; ATP8B1; ATPase phospholipid transporting 8B1

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