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Magic™ Membrane Protein Human BSCL2 (BSCL2 lipid droplet biogenesis associated, seipin) Full Length (CAT#: MPC2956K) Made to Order

Datasheet
This product is a made-to-order Human BSCL2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • BSCL2
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • TMD
  • 2
  • Sequence
  • MVNDPPVPALLWAQEVGQVLAGRARRLLLQFGVLFCTILLLLWVSVFLYG
    SFYYSYMPTVSHLSPVHFYYRTDCDSSTTSLCSFPVANVSLTKGGRDRVL
    MYGQPYRVTLELELPESPVNQDLGMFLVTISCYTRGGRIISTSSRSVMLH
    YRSDLLQMLDTLVFSSLLLFGFAEQKQLLEVELYADYRENSYVPTTGAII
    EIHSKRIQLYGAYLRIHAHFTGLRYLLYNFPMTCAFIGVASNFTFLSVIV
    LFSYMQWVWGGIWPRHRFSLQVNIRKRDNSRKEVQRRISAHQPGPEGQEE
    STPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGSG
    SWEDAALLTEANLPAPAPASASAPVLETLGSSEPAGGALRQRPTCSSS

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • StrepII tag at the N-terminus
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • BSCL2
  • Full Name
  • BSCL2 lipid droplet biogenesis associated, seipin
  • Introduction
  • This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).
  • Alternative Names
  • BSCL2; HMN5; PELD; HMN5C; SPG17; GNG3LG; seipin; BSCL2, seipin lipid droplet biogenesis associated; Berardinelli-Seip congenital lipodystrophy 2 (seipin); Bernardinelli-Seip congenital lipodystrophy type 2 protein; BSCL2 lipid droplet biogenesis associated, seipin

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