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Magic™ Membrane Protein Human CD109 (CD109 molecule) Expressed in NS0 for Antibody Discovery, Partial (22-1268aa, Y703S & T1241M) (CAT#: MPX0801K)

Datasheet
This product is a 141 kDa Human CD109 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CD109
  • Protein Length
  • Partial (22-1268aa, Y703S & T1241M)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 141 kDa
  • Sequence
  • VAPGPRFLVTAPGIIRPGGNVTIGVELLE
    HCPSQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSADE
    IYELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYKPKQEVKFRI
    VTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVISKTFQLSSHPI
    LGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGTI
    TAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMK
    NVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYI
    IEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTE
    YWSGSNSGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGS
    KSSMAVHSLFKSPSKTYIQLKTRDENIKVGSPFELVVSGNKRLKELSYMV
    VSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIP
    VQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMN
    ASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANLTKDY
    IDGVYDNAEYAERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTN
    MGSRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFI
    FLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEIN
    ATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPTASDAVTQMIL
    VKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAI
    GDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLK
    EKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEAD
    PYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTA
    YIVTSLLGYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALSSVG
    SPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPRSLDIEVAAYALL
    SHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNT
    ERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPMAVNISANGF
    GFAICQLNVVYNVKASGS

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • 10xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.01 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • CD109
  • Full Name
  • CD109 molecule
  • Introduction
  • This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • CD109; p180; r150; CPAMD7; CD109 antigen; 150 kDa TGF-beta-1-binding protein; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; Gov platelet alloantigens; activated T-cell marker CD109; platelet-specific Gov antigen; CD109 molecule

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