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Magic™ Membrane Protein Human CDH2 (Cadherin 2) Expressed in NS0 for Antibody Discovery, Partial (160-724aa) (CAT#: MPX0163K)

Datasheet
This product is a 89.2 kDa Human CDH2 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CDH2
  • Protein Length
  • Partial (160-724aa)
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 89.2 kDa
  • TMD
  • 1
  • Sequence
  • DWVIPPINLPENSRGPFPQELVRIRSDRDKNLSLRYSVTGP
    GADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAVDINGNQVENP
    IDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNAL
    NGMLRYRIVSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQ
    ATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENRVDIIV
    ANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPI
    DFETNRMFVLTVAAENQVPLAKGIQHPPQSTATVSVTVIDVNENPYFAPN
    PKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWLKIDPVN
    GQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDIND
    NAPQVLPQEAETCETPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKR
    NWTITRLNGDFAQLNLKIKFLEAGIYEVPIIITDSGNPPKSNISILRVKV
    CQCDSNGDCTDVDRIVGAGLGTGA

Product Description

  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc and 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile, deionized water containing 2 mM calcium 24 hours prior to use.
  • Endotoxin
  • <1.0 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in Tris-Citrate.

Target

  • Target Protein
  • CDH2
  • Full Name
  • Cadherin 2
  • Introduction
  • This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone.
  • Alternative Names
  • CDH2; CDHN; NCAD; ACOGS; CD325; ARVD14; CDw325; cadherin-2; N-cadherin 1; cadherin 2, type 1, N-cadherin (neuronal); calcium-dependent adhesion protein, neuronal; neural cadherin; Cadherin 2

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