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Magic™ Membrane Protein Human CHST8 (Carbohydrate sulfotransferase 8) Full Length (CAT#: MPC4101K) Made to Order

This product is a made-to-order Human CHST8 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CHST8
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • TMD
  • 1
  • Sequence
  • MTLRPGTMRLACMFSSILLFGAAGLLLFISLQDPTELAPQQVPGIKFNIR
    PRQPHHDLPPGGSQDGDLKEPTERVTRDLSSGAPRGRNLPAPDQPQPPLQ
    RGTRLRLRQRRRRLLIKKMPAAATIPANSSDAPFIRPGPGTLDGRWVSLH
    RSQQERKRVMQEACAKYRASSSRRAVTPRHVSRIFVEDRHRVLYCEVPKA
    GCSNWKRVLMVLAGLASSTADIQHNTVHYGSALKRLDTFDRQGILHRLST
    YTKMLFVREPFERLVSAFRDKFEHPNSYYHPVFGKAILARYRANASREAL
    RTGSGVRFPEFVQYLLDVHRPVGMDIHWDHVSRLCSPCLIDYDFVGKFES
    MEDDANFFLSLIRAPRNLTFPRFKDRHSQEARTTARIAHQYFAQLSALQR
    QRTYDFYYMDYLMFNYSKPFADLY

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • CHST8
  • Full Name
  • Carbohydrate sulfotransferase 8
  • Introduction
  • The protein encoded by this gene belongs to the sulfotransferase 2 family. It is predominantly expressed in the pituitary gland, and is localized to the golgi membrane. This protein catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It is responsible for sulfation of GalNAc on luteinizing hormone (LH), which is required for production of the sex hormones. Mice lacking this enzyme, exhibit increased levels of circulating LH, and precocious sexual maturation of both male and female mice. Alternatively spliced transcript variants have been found for this gene.
  • Alternative Names
  • CHST8; PSS3; GalNAc4ST; GALNAC4ST1; GALNAC-4-ST1; GalNAc-4-O-sulfotransferase 1; N-acetylgalactosamine-4-O-sulfotransferase 1; carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8; galNAc4ST-1; Carbohydrate sulfotransferase 8

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