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Magic™ Membrane Protein Human CLCNKA (Chloride voltage-gated channel Ka) Full Length (CAT#: MPC0487K) Made to Order

This product is a 75.2 kDa Human CLCNKA membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CLCNKA
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 75.2 kDa
  • TMD
  • 10
  • Sequence
  • MEELVGLREGFSGDPVTLQELWGPCPHIRRAIQGGLEWLKQKVFRLGEDW
    YFLMTLGVLMALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYP
    VALVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVG
    LSCTLATGSTLFLGKVGPFVHLSVMIAAYLGRVRTTTIGEPENKSKQNEM
    LVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGFFAATCGAFIF
    RLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYL
    FCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGVGHFLAS
    RLSMKQHLDSLFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFG
    TLAFFLVMKFWMLILATTIPMPAGYFMPIFILGAAIGRLLGEALAVAFPE
    GIVTGGVTNPIMPGGYALAGAAAFSGAVTHTISTALLAFELTGQIVHALP
    VLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNIGSHHVRVEHF
    MNHSITTLAKDTPLEEVVKVVTSTDVTEYPLVESTESQILVGIVQRAQLV
    QALQAEPPSRAPGHQQCLQDILARGCPTEPVTLTLFSETTLHQAQNLFKL
    LNLQSLFVTSRGRAVGCVSWVEMKKAISNLTNPPAPK

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • CLCNKA
  • Full Name
  • Chloride voltage-gated channel Ka
  • Introduction
  • This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • CLCK1; ClC-K1; hClC-Ka; chloride channel protein ClC-Ka; chloride channel Ka; chloride channel, kidney, A; chloride channel, voltage-sensitive Ka; CLCNKA; Chloride voltage-gated channel Ka

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