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Magic™ Membrane Protein Human COQ2 (Coenzyme Q2, polyprenyltransferase) Full Length (CAT#: MPC4469K) Made to Order

Datasheet
This product is a made-to-order Human COQ2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • COQ2
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • TMD
  • 9
  • Sequence
  • MLGSRAAGFARGLRALALAWLPGWRGRSFALARAAGAPHGGDLQPPACPE
    PRGRQLSLSAAAVVDSAPRPLQPYLRLMRLDKPIGTWLLYLPCTWSIGLA
    AEPGCFPDWYMLSLFGTGAILMRGAGCTINDMWDQDYDKKVTRTANRPIA
    AGDISTFQSFVFLGGQLTLALGVLLCLNYYSIALGAGSLLLVITYPLMKR
    ISYWPQLALGLTFNWGALLGWSAIKGSCDPSVCLPLYFSGVMWTLIYDTI
    YAHQDKRDDVLIGLKSTALRFGENTKPWLSGFSVAMLGALSLVGVNSGQT
    APYYAALGAVGAHLTHQIYTLDIHRPEDCWNKFISNRTLGLIVFLGIVLG
    NLWKEKKTDKTKKGIENKIEN

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • COQ2
  • Full Name
  • Coenzyme Q2, polyprenyltransferase
  • Introduction
  • This gene encodes an enzyme that functions in the final steps in the biosynthesis of CoQ (ubiquinone), a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. This enzyme, which is part of the coenzyme Q10 pathway, catalyzes the prenylation of parahydroxybenzoate with an all-trans polyprenyl group. Mutations in this gene cause coenzyme Q10 deficiency, a mitochondrial encephalomyopathy, and also COQ2 nephropathy, an inherited form of mitochondriopathy with primary renal involvement.
  • Alternative Names
  • COQ2; MSA1; CL640; COQ10D1; PHB:PPT; 4-hydroxybenzoate polyprenyltransferase, mitochondrial; 4-HB polyprenyltransferase; 4-hydroxybenzoate decaprenyltransferase; PHB:polyprenyltransferase; coenzyme Q2 4-hydroxybenzoate polyprenyltransferase; coenzyme Q2 homolog, prenyltransferase; para-hydroxybenzoate-polyprenyltransferase, mitochondrial; Coenzyme Q2, polyprenyltransferase

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