Close
Close

Magic™ Membrane Protein Human CSE1L (Chromosome segregation 1 like) Expressed in vitro E.coli expression system for Antibody Discovery, Partial (1-200aa) (CAT#: MPX0852K)

Datasheet
This product is a 39.1kDa Human CSE1L membrane protein expressed in vitro E.coli expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CSE1L
  • Protein Length
  • Partial (1-200aa)
  • Protein Class
  • Transport
  • Molecular Weight
  • 39.1kDa
  • Sequence
  • MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLLLTLLEKSQDNVIKVCASVTFKNYIKRNWRIVEDEPNKICEADRVAIKANIVHLMLSSPEQIQKQLSDAISIIGREDFPQKWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALPLTNLFKATIELCSTHAN

Product Description

  • Expression Systems
  • in vitro E.coli expression system
  • Tag
  • 6xHis and SUMO tag at the N-terminus
  • Protein Format
  • Soluble
  • Purity
  • >90% as determined by SDS-PAGE.
  • Buffer
  • Tris/PBS-based buffer, 6% Trehalose, pH 8.0

Target

  • Target Protein
  • CSE1L
  • Full Name
  • Chromosome segregation 1 like
  • Introduction
  • Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene.
  • Alternative Names
  • CSE1L; CAS; CSE1; XPO2; exportin-2; CSE1 chromosome segregation 1-like; cellular apoptosis susceptibility protein; chromosome segregation 1-like protein; epididymis secretory sperm binding protein; exp2; importin-alpha re-exporter; Chromosome segregation 1 like

Customer reviews and Q&As    

Related Products
Online Inquiry
CONTACT US
USA:
Europe:
Germany:
Call us at:
USA:
UK:
Germany:
Fax:
Email:
Our customer service representatives are available 24 hours a day, 7 days a week. Contact Us
© 2024 Creative Biolabs. | Contact Us