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Magic™ Membrane Protein Human DRD3 (Dopamine receptor D3) Full Length (CAT#: MPC0081K) Made to Order

This product is a 44.2 kDa Human DRD3 membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • DRD3
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 44.2 kDa
  • TMD
  • 7
  • Sequence
  • MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLV
    CMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSR
    ICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRV
    ALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLP
    FGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHL
    ELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
    LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHV
    LNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • DRD3
  • Full Name
  • Dopamine receptor D3
  • Introduction
  • This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
  • Alternative Names
  • D3DR; ETM1; FET1; D(3) dopamine receptor; essential tremor 1; DRD3; Dopamine receptor D3

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