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Magic™ Membrane Protein Human ENG (Endoglin) Full Length (CAT#: MPC2064K) Made to Order

Datasheet
This product is a 70.5 kDa Human ENG membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ENG
  • Protein Length
  • Full length
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 70.5 kDa
  • TMD
  • 1
  • Sequence
  • MDRGTLPLAVALLLASCSLSPTSLAETVHCDLQPVGPERGEVTYTTSQVS
    KGCVAQAPNAILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLS
    VNSSVFLHLQALGIPLHLAYNSSLVTFQEPPGVNTTELPSFPKTQILEWA
    AERGPITSAAELNDPQSILLRLGQAQGSLSFCMLEASQDMGRTLEWRPRT
    PALVRGCHLEGVAGHKEAHILRVLPGHSAGPRTVTVKVELSCAPGDLDAV
    LILQGPPYVSWLIDANHNMQIWTTGEYSFKIFPEKNIRGFKLPDTPQGLL
    GEARMLNASIVASFVELPLASIVSLHASSCGGRLQTSPAPIQTTPPKDTC
    SPELLMSLIQTKCADDAMTLVLKKELVAHLKCTITGLTFWDPSCEAEDRG
    DKFVLRSAYSSCGMQVSASMISNEAVVNILSSSSPQRKKVHCLNMDSLSF
    QLGLYLSPHFLQASNTIEPGQQSFVQVRVSPSVSEFLLQLDSCHLDLGPE
    GGTVELIQGRAAKGNCVSLLSPSPEGDPRFSFLLHFYTVPIPKTGTLSCT
    VALRPKTGSQDQEVHRTVFMRLNIISPDLSGCTSKGLVLPAVLGITFGAF
    LIGALLTAALWYIYSHTRSPSKREPVVAVAAPASSESSSTNHSIGSTQST
    PCSTSSMA

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ENG
  • Full Name
  • Endoglin
  • Introduction
  • This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • ENG; END; HHT1; ORW1; CD105 antigen; Endoglin

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