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Magic™ Membrane Protein Human EPHA4 (EPH receptor A4) Expressed in NS0 for Antibody Discovery, Partial (1-547aa) (CAT#: MPX0092K)

Datasheet
This product is a 85 kDa Human EPHA4 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • EPHA4
  • Protein Length
  • Partial (1-547aa)
  • Protein Class
  • Transporter
  • Molecular Weight
  • 85 kDa
  • TMD
  • 1
  • Sequence
  • MAGIFYFALFSCLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPL
    EGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIE
    IKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKIDTIAA
    DESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVF
    YKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCGAD
    GEWLVPIGNCLCNAGHEERSGECQACKIGYYKALSTDATCAKCPPHSYSV
    WEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSS
    PQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTKVSI
    TDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQAAPSSIALVQAK
    EVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDI
    KGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANST

Product Description

  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • EPHA4
  • Full Name
  • EPH receptor A4
  • Introduction
  • This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • EPHA4; EK8; SEK; HEK8; TYRO1; ephrin type-A receptor 4; EPH-like kinase 8; TYRO1 protein tyrosine kinase; receptor protein-tyrosine kinase HEK8; tyrosine-protein kinase TYRO1; tyrosine-protein kinase receptor SEK; EPH receptor A4

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