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Magic™ Membrane Protein Human ERLIN1 (ER lipid raft associated 1) Expressed in vitro E.coli expression system, Full Length (CAT#: MPX0899K)

Datasheet
This product is a Human ERLIN1 membrane protein expressed in vitro E.coli expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ERLIN1
  • Protein Length
  • Full Length
  • Protein Class
  • Receptor
  • Molecular Weight
  • 42.0 kDa
  • TMD
  • 1
  • Sequence
  • MNMTQARVLVAAVVGLVAVLLYASIHKIEEGHLAVYYRGGALLTSPSGPGYHIMLPFITTFRSVQTTLQTDEVKNVPCGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFNKIHHELNQFCSAHTLQEVYIELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEAIRRNFELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQKVMEKETEKRISEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPEYLELKKYQAIASNSKIYFGSNIPNMFVDSSCALKYSDIRTGRESSLPSKEALEPSGENVIQNKESTG

Product Description

  • Expression Systems
  • in vitro E.coli expression system
  • Tag
  • 10xHis tag at the N-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute protein in deionized sterile water
  • Purity
  • >85% as determined by SDS-PAGE.
  • Buffer
  • Tris/PBS-based buffer, 6% Trehalose, pH 8.0

Target

  • Target Protein
  • ERLIN1
  • Full Name
  • ER lipid raft associated 1
  • Introduction
  • The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62.
  • Alternative Names
  • ERLIN1; KE04; KEO4; SPFH1; SPG62; Erlin-1; C10orf69; erlin-1; Band_7 23-211 Keo4 (Interim) similar to C.elegans protein C42C1.9; SPFH domain family, member 1; SPFH domain-containing protein 1; endoplasmic reticulum lipid raft-associated protein 1; stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1; ER lipid raft associated 1

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