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Magic™ Membrane Protein Human GUCY2C (Guanylate cyclase 2C) Full Length (CAT#: MPC1713K) Made to Order

This product is a 123.4 kDa Human GUCY2C membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GUCY2C
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • Molecular Weight
  • 123.4 kDa
  • TMD
  • 1
  • Sequence
  • MKTLLLDLALWSLLFQPGWLSFSSQVSQNCHNGSYEISVLMMGNSAFAEP
    LKNLEDAVNEGLEIVRGRLQNAGLNVTVNATFMYSDGLIHNSGDCRSSTC
    EGLDLLRKISNAQRMGCVLIGPSCTYSTFQMYLDTELSYPMISAGSFGLS
    CDYKETLTRLMSPARKLMYFLVNFWKTNDLPFKTYSWSTSYVYKNGTETE
    DCFWYLNALEASVSYFSHELGFKVVLRQDKEFQDILMDHNRKSNVIIMCG
    GPEFLYKLKGDRAVAEDIVIILVDLFNDQYFEDNVTAPDYMKNVLVLTLS
    PGNSLLNSSFSRNLSPTKRDFALAYLNGILLFGHMLKIFLENGENITTPK
    FAHAFRNLTFEGYDGPVTLDDWGDVDSTMVLLYTSVDTKKYKVLLTYDTH
    VNKTYPVDMSPTFTWKNSKLPNDITGRGPQILMIAVFTLTGAVVLLLLVA
    LLMLRKYRKDYELRQKKWSHIPPENIFPLETNETNHVSLKIDDDKRRDTI
    QRLRQCKYDKKRVILKDLKHNDGNFTEKQKIELNKLLQIDYYNLTKFYGT
    VKLDTMIFGVIEYCERGSLREVLNDTISYPDGTFMDWEFKISVLYDIAKG
    MSYLHSSKTEVHGRLKSTNCVVDSRMVVKITDFGCNSILPPKKDLWTAPE
    HLRQANISQKGDVYSYGIIAQEIILRKETFYTLSCRDRNEKIFRVENSNG
    MKPFRPDLFLETAEEKELEVYLLVKNCWEEDPEKRPDFKKIETTLAKIFG
    LFHDQKNESYMDTLIRRLQLYSRNLEHLVEERTQLYKAERDRADRLNFML
    LPRLVVKSLKEKGFVEPELYEEVTIYFSDIVGFTTICKYSTPMEVVDMLN
    DIYKSFDHIVDHHDVYKVETIGDAYMVASGLPKRNGNRHAIDIAKMALEI
    LSFMGTFELEHLPGLPIWIRIGVHSGPCAAGVVGIKMPRYCLFGDTVNTA
    SRMESTGLPLRIHVSGSTIAILKRTECQFLYEVRGETYLKGRGNETTYWL
    TGMKDQKFNLPTPPTVENQQRLQAEFSDMIANSLQKRQAAGIRSQKPRRV
    ASYKKGTLEYLQLNTTDKESTYF

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • GUCY2C
  • Full Name
  • Guanylate cyclase 2C
  • Introduction
  • This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive).
  • Alternative Names
  • GUCY2C; GC-C; STAR; DIAR6; GUC2C; MECIL; MUCIL; heat-stable enterotoxin receptor; STA receptor; guanylyl cyclase C; intestinal guanylate cyclase; Guanylate cyclase 2C

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