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Magic™ Membrane Protein Human HM13 (Histocompatibility minor 13) Full Length (CAT#: MPC2274K) Made to Order

This product is a 41.4 kDa Human HM13 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • HM13
  • Protein Length
  • Full length
  • Protein Class
  • Protease
  • Molecular Weight
  • 41.4 kDa
  • TMD
  • 9
  • Sequence
  • MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFG
    ALRSVRCARGKNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEY
    INLLLSMYFFVLGILALSHTISPFMNKFFPASFPNRQYQLLFTQGSGENK
    EEIINYEFDTKDLVCLGLSSIVGVWYLLRKHWIANNLFGLAFSLNGVELL
    HLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPIKLVFPQDLLE
    KGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIF
    GLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYEESN
    PKDPAAVTESKEGTEASASKGLEKKEK

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • StrepII and Flag tag at the N-terminus
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • HM13
  • Full Name
  • Histocompatibility minor 13
  • Introduction
  • The protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene.
  • Alternative Names
  • HM13; H13; SPP; IMP1; PSL3; IMPAS; SPPL1; PSENL3; IMPAS-1; MSTP086; minor histocompatibility antigen H13; intramembrane protease 1; minor histocompatibility antigen 13; presenilin-like protein 3; signal peptide peptidase beta; signal peptide peptidase like 1; Histocompatibility minor 13

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