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Magic™ Membrane Protein Human IL18R1 (Interleukin 18 receptor 1) Expressed in NS0 for Antibody Discovery, Partial (20-329aa) (CAT#: MPX0453K)

Datasheet
This product is a 63 kDa Human IL18R1 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IL18R1
  • Protein Length
  • Partial (20-329aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 63 kDa
  • TMD
  • 1
  • Sequence
  • ESCTSRPHITVVEGEPFYLKHCSCSLAHEIE
    TTTKSWYKSSGSQEHVELNPRSSSRIALHDCVLEFWPVELNDTGSYFFQM
    KNYTQKWKLNVIRRNKHSCFTERQVTSKIVEVKKFFQITCENSYYQTLVN
    STSLYKNCKKLLLENNKNPTIKKNAEFEDQGYYSCVHFLHHNGKLFNITK
    TFNITIVEDRSNIVPVLLGPKLNHVAVELGKNVRLNCSALLNEEDVIYWM
    FGEENGSDPNIHEEKEMRIMTPEGKWHASKVLRIENIGESNLNVLYNCTV
    ASTGGTDTKSFILVRKADMADIPGHVFTR

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc and 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 1 mg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • IL18R1
  • Full Name
  • Interleukin 18 receptor 1
  • Introduction
  • The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • IL18R1; CD218a; IL18RA; IL1RRP; CDw218a; IL-1Rrp; IL-18Ralpha; IL18Ralpha2; IL-18R-alpha; interleukin-18 receptor 1; CD218 antigen-like family member A; IL1 receptor-related protein; cytokine receptor; interleukin-18 receptor alpha; Interleukin 18 receptor 1

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