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Magic™ Membrane Protein Human ITGA2 (Integrin subunit alpha 2) Expressed in E.coli with 6xHis and SUMO tag at the N-terminus for Antibody Discovery, Partial (188-365aa) (CAT#: MPX4582K)

Datasheet
This product is a 35.6kDa Human ITGA2 membrane protein expressed in E.coli. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ITGA2
  • Protein Length
  • Partial (188-365aa)
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 35.6kDa
  • TMD
  • 1
  • Sequence
  • WDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIE

Product Description

  • Expression Systems
  • E.coli
  • Tag
  • 6xHis and SUMO tag at the N-terminus
  • Protein Format
  • Soluble
  • Purity
  • >90% as determined by SDS-PAGE
  • Buffer
  • Tris-based buffer, 50% glycerol

Target

  • Target Protein
  • ITGA2
  • Full Name
  • Integrin subunit alpha 2
  • Introduction
  • This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • ITGA2; BR; GPIa; CD49B; HPA-5; VLA-2; VLAA2; integrin alpha-2; CD49 antigen-like family member B; alpha 2 subunit of VLA-2 receptor; collagen receptor; human platelet alloantigen system 5; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); platelet antigen Br; platelet glycoprotein GPIa; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit; Integrin subunit alpha 2

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