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Magic™ Membrane Protein Human IYD (Iodotyrosine deiodinase) Full Length (CAT#: MPC3730K) Made to Order

This product is a made-to-order Human IYD membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IYD
  • Protein Length
  • Full length
  • Protein Class
  • Oxidoreductase
  • TMD
  • 1
  • Sequence
  • MYFLTPILVAILCILVVWIFKNADRSMEKKKGEPRTRAEARPWVDEDLKD
    SSDLHQAEEDADEWQESEENVEHIPFSHNHYPEKEMVKRSQEFYELLNKR
    RSVRFISNEQVPMEVIDNVIRTAGTAPSGAHTEPWTFVVVKDPDVKHKIR
    KIIEEEEEINYMKRMGHRWVTDLKKLRTNWIKEYLDTAPILILIFKQVHG
    FAANGKKKVHYYNEISVSIACGILLAALQNAGLVTVTTTPLNCGPRLRVL
    LGRPAHEKLLMLLPVGYPSKEATVPDLKRKPLDQIMVTV

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • IYD
  • Full Name
  • Iodotyrosine deiodinase
  • Introduction
  • This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • IYD; TDH4; IYD-1; DEHAL1; C6orf71; iodotyrosine dehalogenase 1; Iodotyrosine deiodinase

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