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Magic™ Membrane Protein Human JAM2 (Junctional adhesion molecule 2) Expressed in NS0 for Antibody Discovery, Partial (29-236aa) (CAT#: MPX0651K)

Datasheet
This product is a 50 kDa Human JAM2 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • JAM2
  • Protein Length
  • Partial (29-236aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 50 kDa
  • TMD
  • 1
  • Sequence
  • FSAPKDQQVVTAVEYQEAILAC
    KTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVT
    RSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTV
    VELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQ
    FNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLN

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • JAM2
  • Full Name
  • Junctional adhesion molecule 2
  • Introduction
  • This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene.
  • Alternative Names
  • JAM2; JAMB; CD322; IBGC8; JAM-B; VEJAM; PRO245; VE-JAM; C21orf43; JAM-2; JAM-IT/VE-JAM; vascular endothelial junction-associated molecule; Junctional adhesion molecule 2

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