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Magic™ Membrane Protein Human KCNJ2 (Potassium inwardly rectifying channel subfamily J member 2) Full Length (CAT#: MPC0609K) Made to Order

Datasheet
This product is a 48.2 kDa Human KCNJ2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCNJ2
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 48.2 kDa
  • TMD
  • 2
  • Sequence
  • MGSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKK
    DGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFG
    CVFWLIALLHGDLDASKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCV
    TDECPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAV
    IAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDI
    NVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEG
    MVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEV
    PNTPLCSARDLAEKKYILSNANSFCYENEVALTSKEEDDSENGVPESTST
    DTPPDIDLHNQASVPLEPRPLRRESEI

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • KCNJ2
  • Full Name
  • Potassium inwardly rectifying channel subfamily J member 2
  • Introduction
  • Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features.
  • Alternative Names
  • IRK1; LQT7; SQT3; ATFB9; HHIRK1; KIR2.1; HHBIRK1; inward rectifier potassium channel 2; IRK-1; cardiac inward rectifier potassium channel; hIRK1; inward rectifier K+ channel KIR2.1; potassium channel, inwardly rectifying subfamily J, member 2; potassium voltage-gated channel subfamily J member 2; KCNJ2; Potassium inwardly rectifying channel subfamily J member 2

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