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Magic™ Membrane Protein Human KCNJ5 (Potassium inwardly rectifying channel subfamily J member 5) Full Length (CAT#: MPC0612K) Made to Order

Datasheet
This product is a 47.6 kDa Human KCNJ5 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCNJ5
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 47.6 kDa
  • TMD
  • 2
  • Sequence
  • MAGDSRNAMNQDMEIGVTPWDPKKIPKQARDYVPIATDRTRLLAEGKKPR
    QRYMEKSGKCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVT
    WLFFGFIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTI
    GYGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETL
    MFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFI
    PLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSPFWEMSQAQLHQEEFE
    VVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNT
    FHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQ
    NEEDEPKGLGGSREARGSV

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • KCNJ5
  • Full Name
  • Potassium inwardly rectifying channel subfamily J member 5
  • Introduction
  • This gene encodes an integral membrane protein which belongs to one of seven subfamilies of inward-rectifier potassium channel proteins called potassium channel subfamily J. The encoded protein is a subunit of the potassium channel which is homotetrameric. It is controlled by G-proteins and has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Naturally occurring mutations in this gene are associated with aldosterone-producing adenomas.
  • Alternative Names
  • CIR; GIRK4; KATP1; LQT13; KIR3.4; G protein-activated inward rectifier potassium channel 4; IRK-4; cardiac ATP-sensitive potassium channel; heart KATP channel; inward rectifier K+ channel KIR3.4; potassium channel, inwardly rectifying subfamily J, member 5; potassium voltage-gated channel subfamily J member 5; KCNJ5; Potassium inwardly rectifying channel subfamily J member 5

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