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Magic™ Membrane Protein Human MBTPS2 (Membrane bound transcription factor peptidase, site 2) Full Length (CAT#: MPC1941K) Made to Order

Datasheet
This product is a 57.4 kDa Human MBTPS2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MBTPS2
  • Protein Length
  • Full length
  • Protein Class
  • Protease
  • Molecular Weight
  • 57.4 kDa
  • TMD
  • 10
  • Sequence
  • MIPVSLVVVVVGGWTVVYLTDLVLKSSVYFKHSYEDWLENNGLSISPFHI
    RWQTAVFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQ
    TLAQMMADSPSSYSSSSSSSSSSSSSSSSSSSSSSSLHNEQVLQVVVPGI
    NLPVNQLTYFFTAVLISGVVHEIGHGIAAIREQVRFNGFGIFLFIIYPGA
    FVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFY
    YTGVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDWNECLDTI
    AYEPQIGYCISASTLQQLSFPVRAYKRLDGSTECCNNHSLTDVCFSYRNN
    FNKRLHTCLPARKAVEATQVCRTNKDCKKSSSSSFCIIPSLETHTRLIKV
    KHPPQIDMLYVGHPLHLHYTVSITSFIPRFNFLSIDLPVVVETFVKYLIS
    LSGALAIVNAVPCFALDGQWILNSFLDATLTSVIGDNDVKDLIGFFILLG
    GSVLLAANVTLGLWMVTAR

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • MBTPS2
  • Full Name
  • Membrane bound transcription factor peptidase, site 2
  • Introduction
  • This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.
  • Alternative Names
  • MBTPS2; S2P; IFAP; KFSD; OI19; KFSDX; OLMSX; BRESEK; membrane-bound transcription factor site-2 protease; SREBPs intramembrane protease; endopeptidase S2P; keratosis follicularis spinulosa decalvans; membrane-bound transcription factor protease, site 2; site-2 protease; sterol regulatory element-binding proteins intramembrane protease; Membrane bound transcription factor peptidase, site 2

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