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Magic™ Membrane Protein Human MCOLN1 (Mucolipin TRP cation channel 1) Full Length (CAT#: MPC0662K) Made to Order

Datasheet
This product is a 65 kDa Human MCOLN1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MCOLN1
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 65 kDa
  • TMD
  • 6
  • Sequence
  • MTAPAGPRGSETERLLTPNPGYGTQAGPSPAPPTPPEEEDLRRRLKYFFM
    SPCDKFRAKGRKPCKLMLQVVKILVVTVQLILFGLSNQLAVTFREENTIA
    FRHLFLLGYSDGADDTFAAYTREQLYQAIFHAVDQYLALPDVSLGRYAYV
    RGGGDPWTNGSGLALCQRYYHRGHVDPANDTFDIDPMVVTDCIQVDPPER
    PPPPPSDDLTLLESSSSYKNLTLKFHKLVNVTIHFRLKTINLQSLINNEI
    PDCYTFSVLITFDNKAHSGRIPISLETQAHIQECKHPSVFQHGDNSFRLL
    FDVVVILTCSLSFLLCARSLLRGFLLQNEFVGFMWRQRGRVISLWERLEF
    VNGWYILLVTSDVLTISGTIMKIGIEAKNLASYDVCSILLGTSTLLVWVG
    VIRYLTFFHNYNILIATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPY
    HVKFRSLSMVSECLFSLINGDDMFVTFAAMQAQQGRSSLVWLFSQLYLYS
    FISLFIYMVLSLFIALITGAYDTIKHPGGAGAEESELQAYIAQCQDSPTS
    GKFRRGSGSACSLLCCCGRDPSEEHSLLVN

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag tag at the N-terminus
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • MCOLN1
  • Full Name
  • Mucolipin TRP cation channel 1
  • Introduction
  • This gene encodes a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca(2+), Fe(2+), Na(+), K(+), and H(+), and is modulated by changes in Ca(2+) concentration. Mutations in this gene result in mucolipidosis type IV.
  • Alternative Names
  • ML1; ML4; MG-2; MLIV; MST080; TRPML1; MSTP080; TRP-ML1; TRPM-L1; mucolipin-1; mucolipidin; mucolipidosis type IV protein; mucolipin 1; transient receptor potential cation channel mucolipin subfamily member 1; transient receptor potential channel mucolipin 1; transient receptor potential mucolipin 1; MCOLN1; Mucolipin TRP cation channel 1

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