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Magic™ Membrane Protein Human MUSK (Muscle associated receptor tyrosine kinase) Expressed in HEK293 for Antibody Discovery, Partial (24-495aa) (CAT#: MPX0096K)

Datasheet
This product is a 78 kDa Human MUSK membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MUSK
  • Protein Length
  • Partial (24-495aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 78 kDa
  • TMD
  • 1
  • Sequence
  • LPKAPVITTPLETVDALVEEVATFMCA
    VESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCT
    ANNGVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVLPCTTMGNPKP
    SVSWIKGDSPLRENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLGTAY
    SKVVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGN
    AVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAAT
    ISIAEWSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQEL
    LVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLA
    VKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARL
    PHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMT

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 500 μg/mL in PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • MUSK
  • Full Name
  • Muscle associated receptor tyrosine kinase
  • Introduction
  • This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.
  • Alternative Names
  • MUSK; CMS9; FADS; FADS1; muscle, skeletal receptor tyrosine-protein kinase; muscle, skeletal, receptor tyrosine kinase; muscle-specific kinase receptor; muscle-specific tyrosine-protein kinase receptor; Muscle associated receptor tyrosine kinase

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