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Magic™ Membrane Protein Human NDUFS8 (NADH:ubiqui oxidoreductase core subunit S8) for Antibody Discovery (CAT#: MP0785X)

Datasheet
This product is a 50.1 kDa Human NDUFS8 membrane protein expressed in in vitro wheat germ expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • NDUFS8
  • Protein Length
  • Full-length
  • Molecular Weight
  • 50.1 kDa
  • Sequence
  • MRCLTTPMLLRALAQAARAGPPGGRSLHSSAVAATYKYVNMQDPEMDMKSVTDRAARTLLWTELFRGLGMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLNNGDKWEAEIAANIQADYLYR

Product Description

  • Application
  • Enzyme-linked Immunoabsorbent Assay, Western Blot (Recombinant protein), Antibody Production, Protein Array
  • Expression Systems
  • in vitro wheat germ expression system
  • Tag
  • GST-tag at N-terminal
  • Purification
  • Glutathione Sepharose 4 Fast Flow
  • Buffer
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer

Target

  • Target Protein
  • NDUFS8
  • Full Name
  • NADH:ubiqui oxidoreductase core subunit S8
  • Introduction
  • This gene encodes a subunit of mitochondrial NADH:ubiqui oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiqui reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome.
  • Alternative Names
  • TYKY; CI-23k; CI23KD; MC1DN2; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial; NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase); NADH-ubiquinone oxidoreductase 23 kDa subunit; complex I 23kDa subunit; complex I-23kD; CI-23kD; NADH-ubiquinone oxidoreductase 23 kDa subunit; TYKY subunit

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