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Magic™ Membrane Protein Human P4HTM (Prolyl 4-hydroxylase, transmembrane) Expressed in E.coli with 6xHis and SUMO tag at the N-terminus for Antibody Discovery, Partial (82-563aa) (CAT#: MPX4505K)

Datasheet
This product is a 70.5kDa Human P4HTM membrane protein expressed in E.coli. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • P4HTM
  • Protein Length
  • Partial (82-563aa)
  • Protein Class
  • Oxidoreductase
  • Molecular Weight
  • 70.5kDa
  • TMD
  • 1
  • Sequence
  • VHYSNGDESSDPGPQHRAQGPGPEPTLGPLTRLEGIKVGHERKVQLVTDRDHFIRTLSLKPLLFEIPGFLTDEECRLIIHLAQMKGLQRSQILPTEEYEEAMSTMQVSQLDLFRLLDQNRDGHLQLREVLAQTRLGNGWWMTPESIQEMYAAIKADPDGDGVLSLQEFSNMDLRDFHKYMRSHKAESSELVRNSHHTWLYQGEGAHHIMRAIRQRVLRLTRLSPEIVELSEPLQVVRYGEGGHYHAHVDSGPVYPETICSHTKLVANESVPFETSCRQVSPNWGLPSILRPGTPMTQAQPCTVGVPLGMGPGDHWVIPVSPWEHPQLGTCSVPPLPYSYMTVLFYLNNVTGGGETVFPVADNRTYDEMSLIQDDVDLRDTRRHCDKGNLRVKPQQGTAVFWYNYLPDGQGWVGDVDDYSLHGGCLVTRGTKWIANNWINVDPSRARQALFQQEMARLAREGGTDSQPEWALDRAYRDARVEL

Product Description

  • Expression Systems
  • E.coli
  • Tag
  • 6xHis and SUMO tag at the N-terminus
  • Protein Format
  • Soluble
  • Purity
  • >90% as determined by SDS-PAGE
  • Buffer
  • Tris-based buffer, 50% glycerol

Target

  • Target Protein
  • P4HTM
  • Full Name
  • Prolyl 4-hydroxylase, transmembrane
  • Introduction
  • The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified.
  • Alternative Names
  • P4HTM; PH4; PH-4; PHD4; EGLN4; HIDEA; HIFPH4; P4H-TM; transmembrane prolyl 4-hydroxylase; HIF-PH4; HIF-prolyl hydroxylase 4; HPH-4; P4H with transmembrane domain; Prolyl hydroxlase domain-containing 4; hypoxia-inducible factor prolyl 4-hydroxylase; hypoxia-inducible factor prolyl hydroxylase 4; proline 4-hydroxylase; prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum); Prolyl 4-hydroxylase, transmembrane

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