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Magic™ Membrane Protein Human RNF103 (Ring finger protein 103) Full Length (CAT#: MPC4709K) Made to Order

Datasheet
This product is a made-to-order Human RNF103 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • RNF103
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • TMD
  • 4
  • Sequence
  • MWLKLFFLLLYFLVLFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKT
    ILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTN
    FSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKIHWEKMVKKVSRFGIR
    TGTFNCSSDPRYCRRRGWVRSTLIMSVPQTSTSKGKVMLKEYSGRKIEVE
    HIFKWITAHAASRIKTIYNAEHLKEEWNKSDQYWLKIYLFANLDQPPAFF
    SALSIKFTGRVEFIFVNVENWDNKSYMTDIGIYNMPSYILRTPEGIYRYG
    NHTGEFISLQAMDSFLRSLQPEVNDLFVLSLVLVNLMAWMDLFITQGATI
    KRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYEYSLKLLRYSNTT
    TLASWVRADWMFYSSHPALFLSTYLGHGLLIDYFEKKRRRNNNNDEVNAN
    NLEWLSSLWDWYTSYLFHPIASFQNFPVESDWDEDPDLFLERLAFPDLWL
    HPLIPTDYIKNLPMWRFKCLGVQSEEEMSEGSQDTENDSESENTDTLSSE
    KEVFEDKQSVLHNSPGTASHCDAEACSCANKYCQTSPCERKGRSYGSYNT
    NEDMEPDWLTWPADMLHCTECVVCLENFENGCLLMGLPCGHVFHQNCIVM
    WLAGGRHCCPVCRWPSYKKKQPYAQHQPLSNDVPS

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • RNF103
  • Full Name
  • Ring finger protein 103
  • Introduction
  • The protein encoded by this gene contains a RING-H2 finger, a motif known to be involved in protein-protein and protein-DNA interactions. This gene is highly expressed in normal cerebellum, but not in the cerebral cortex. The expression of the rat counterpart in the frontal cortex and hippocampus was shown to be induced by elctroconvulsive treatment (ECT) as well as chronic antidepressant treatment, suggesting that this gene may be a molecular target for ECT and antidepressants. The protein is a ubiquitin ligase that functions in the endoplasmic reticulum-associated degradation pathway. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream CHMP3 (charged multivesicular body protein 3) gene.
  • Alternative Names
  • RNF103; KF1; KF-1; HKF-1; ZFP103; ZFP-103; E3 ubiquitin-protein ligase RNF103; RING-type E3 ubiquitin transferase RNF103; zinc finger protein 103 homolog; zinc finger protein expressed in cerebellum; Ring finger protein 103

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