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Magic™ Membrane Protein Human RYK (Receptor like tyrosine kinase) Full Length (CAT#: MPC1430K) Made to Order

Datasheet
This product is a 67.8 kDa Human RYK membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • RYK
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • Molecular Weight
  • 67.8 kDa
  • TMD
  • 1
  • Sequence
  • MRGAARLGRPGRSCLPGARGLRAPPPPPLLLLLALLPLLPAPGAAAAPAP
    RPPELQSASAGPSVSLYLSEDEVRRLIGLDAELYYVRNDLISHYALSFSL
    LVPSETNFLHFTWHAKSKVEYKLGFQVDNVLAMDMPQVNISVQGEVPRTL
    SVFRVELSCTGKVDSEVMILMQLNLTVNSSKNFTVLNFKRRKMCYKKLEE
    VKTSALDKNTSRTIYDPVHAAPTTSTRVFYISVGVCCAVIFLVAIILAVL
    HLHSMKRIELDDSISASSSSQGLSQPSTQTTQYLRADTPNNATPITSYPT
    LRIEKNDLRSVTLLEAKGKVKDIAISRERITLKDVLQEGTFGRIFHGILI
    DEKDPNKEKQAFVKTVKDQASEIQVTMMLTESCKLRGLHHRNLLPITHVC
    IEEGEKPMVILPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHMAIQIA
    CGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLFPMDYHCLGD
    NENRPVRWMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFE
    MAAYLKDGYRIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFH
    AALGAYV

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • RYK
  • Full Name
  • Receptor like tyrosine kinase
  • Introduction
  • The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
  • Alternative Names
  • RYK; JTK5; RYK1; JTK5A; D3S3195; tyrosine-protein kinase RYK; JTK5A protein tyrosine kinase; hydroxyaryl-protein kinase; Receptor like tyrosine kinase

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