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Magic™ Membrane Protein Human SELE (Selectin E) Expressed in NS0 for Antibody Discovery, Partial (22-556aa) (CAT#: MPX0290K)

Datasheet
This product is a 86 kDa Human SELE membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SELE
  • Protein Length
  • Partial (22-556aa)
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 86 kDa
  • TMD
  • 1
  • Sequence
  • WSYNTSTEAMTYDEASAYCQQRYTHLVAI
    QNKEEIEYLNSILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKNWAPG
    EPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLALCYTAACTNTSCSG
    HGECVETINNYTCKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLGNF
    SYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPAN
    GFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCK
    AVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECT
    TQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQ
    GFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGE
    FTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPG
    KINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAP
    TESNIP

Product Description

  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc and 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 1 mg/mL in sterile, deionized water.
  • Endotoxin
  • <0.1 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • SELE
  • Full Name
  • Selectin E
  • Introduction
  • The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
  • Alternative Names
  • SELE; ELAM; ESEL; CD62E; ELAM1; LECAM2; E-selectin; CD62 antigen-like family member E; ELAM-1; endothelial adhesion molecule 1; endothelial leukocyte adhesion molecule 1; leukocyte endothelial cell adhesion molecule 2; Selectin E

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