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Magic™ Membrane Protein Human SEMA4G (Semaphorin 4G) Expressed in NS0 for Antibody Discovery, Partial (18-675aa) (CAT#: MPX0252K)

Datasheet
This product is a 99 kDa Human SEMA4G membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SEMA4G
  • Protein Length
  • Partial (18-675aa)
  • Protein Class
  • Transporter
  • Molecular Weight
  • 99 kDa
  • TMD
  • 1
  • Sequence
  • VPGPSLRRPSRELDATPRMTIPYEELSGTRHFK
    GQAQNYSTLLLEEASARLLVGARGALFSLSANDIGDGAHKEIHWEASPEM
    QSKCHQKGKNNQTECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDAEAF
    TLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPDIRRSRHP
    HSLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEG
    SGSFTQSRSSHRVARVARVCKGDLGGKKILQKKWTSFLKARLICHIPLYE
    TLRGVCSLDAETSSRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAG
    PYMEYQDGSRRWGRYEGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDF
    VKLHPLMARPVVPTRGRPLLLKRNIRYTHLTGTPVTTPAGPTYDLLFLGT
    ADGWIHKAVVLGSGMHIIEETQVFRESQSVENLVISLLQHSLYVGAPSGV
    IQLPLSSCSRYRSCYDCILARDPYCGWDPGTHACAAATTIANRTALIQDI
    ERGNRGCESSRDTGPPPPLKTRSVLRGDDVLLPCDQPSNLARALWLLNGS
    MGLSDGQGGYRVGVDGLLVTDAQPEHSGNYGCYAEENGLRTLLASYSLTV
    RPATPAPAPKAPATPGAQLAPDVRL

Product Description

  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 200 μg/mL in PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • SEMA4G
  • Full Name
  • Semaphorin 4G
  • Introduction
  • Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • SEMA4G; semaphorin-4G; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G; Semaphorin 4G

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