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Magic™ Membrane Protein Human SEMA5B (Semaphorin 5B) Expressed in CHO for Antibody Discovery, Partial (78-834aa) (CAT#: MPX0224K)

This product is a 110.3 kDa Human SEMA5B membrane protein expressed in CHO. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SEMA5B
  • Protein Length
  • Partial (78-834aa)
  • Protein Class
  • Transporter
  • Molecular Weight
  • 110.3 kDa
  • TMD
  • 1
  • Sequence
  • VSHLSSSQDVSSEPSSEQQLCAL
    SKHPTVAFEDLQPWVSNFTYPGARDFSQLALDPSGNQLIVGARNYLFRLS
    LANVSLLQATEWASSEDTRRSCQSKGKTEEECQNYVRVLIVAGRKVFMCG
    TNAFSPMCTSRQVGNLSRTIEKINGVARCPYDPRHNSTAVISSQGELYAA
    TVIDFSGRDPAIYRSLGSGPPLRTAQYNSKWLNEPNFVAAYDIGLFAYFF
    LRENAVEHDCGRTVYSRVARVCKNDVGGRFLLEDTWTTFMKARLNCSRPG
    EVPFYYNELQSAFHLPEQDLIYGVFTTNVNSIAASAVCAFNLSAISQAFN
    GPFRYQENPRAAWLPIANPIPNFQCGTLPETGPNENLTERSLQDAQRLFL
    MSEAVQPVTPEPCVTQDSVRFSHLVVDLVQAKDTLYHVLYIGTESGTILK
    ALSTASRSLHGCYLEELHVLPPGRREPLRSLRILHSARALFVGLRDGVLR
    VPLERCAAYRSQGACLGARDPYCGWDGKQQRCSTLEDSSNMSLWTQNITA
    CPVRNVTRDGGFGPWSPWQPCEHLDGDNSGSCLCRARSCDSPRPRCGGLD
    CLGPAIHIANCSRNGAWTPWSSWALCSTSCGIGFQVRQRSCSNPAPRHGG
    RICVGKSREERFCNENTPCPVPIFWASWGSWSKCSSNCGGGMQSRRRACE
    NGNSCLGCGVEFKTCNPEGCPEVRRNTPWTPWLPVNVTQGGARQEQRFRF
    TCRAPLADPHGLQFGRRRTETRTCPADGSGSCDT

Product Description

  • Expression Systems
  • CHO
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 250 μg/mL in PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • SEMA5B
  • Full Name
  • Semaphorin 5B
  • Introduction
  • This gene encodes a member of the semaphorin protein family which regulates axon growth during development of the nervous system. The encoded protein has a characteristic Sema domain near the N-terminus, through which semaphorins bind to plexin, and five thrombospondin type 1 repeats in the C-terminal region of the protein. The protein product may be cleaved and exist as a secreted molecule (PMID: 19463192). Multiple transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • SEMA5B; SemG; SEMAG; semaphorin-5B; sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B; Semaphorin 5B

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