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Magic™ Membrane Protein Human SGMS2 (Sphingomyelin synthase 2) Full Length (CAT#: MPC4767K) Made to Order

This product is a made-to-order Human SGMS2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SGMS2
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • TMD
  • 6
  • Sequence
  • MDIIETAKLEEHLENQPSDPTNTYARPAEPVEEENKNGNGKPKSLSSGLR
    KGTKKYPDYIQIAMPTESRNKFPLEWWKTGIAFIYAVFNLVLTTVMITVV
    HERVPPKELSPPLPDKFFDYIDRVKWAFSVSEINGIILVGLWITQWLFLR
    YKSIVGRRFCFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKV
    QRILRLISGGGLSITGSHILCGDFLFSGHTVTLTLTYLFIKEYSPRHFWW
    YHLICWLLSAAGIICILVAHEHYTIDVIIAYYITTRLFWWYHSMANEKNL
    KVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKK

    YSRVQKIGEDNEKST

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • SGMS2
  • Full Name
  • Sphingomyelin synthase 2
  • Introduction
  • Sphingomyelin, a major component of cell and Golgi membranes, is made by the transfer of phosphocholine from phosphatidylcholine onto ceramide, with diacylglycerol as a side product. The protein encoded by this gene is an enzyme that catalyzes this reaction primarily at the cell membrane. The synthesis is reversible, and this enzyme can catalyze the reaction in either direction. The encoded protein is required for cell growth. Three transcript variants encoding the same protein have been found for this gene. There is evidence for more variants, but the full-length nature of their transcripts has not been determined.
  • Alternative Names
  • SGMS2; CDL; SMS2; phosphatidylcholine:ceramide cholinephosphotransferase 2; SM synthase; Sphingomyelin synthase 2

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