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Magic™ Membrane Protein Human SLAMF6 (SLAM family member 6) Full Length (CAT#: MPC2284K) Made to Order

Datasheet
This product is a 37.3 kDa Human SLAMF6 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLAMF6
  • Protein Length
  • Full length
  • Protein Class
  • Receptor; Immunity
  • Molecular Weight
  • 37.3 kDa
  • TMD
  • 1
  • Sequence
  • MLWLFQSLLFVFCFGPGNVVSQSSLTPLMVNGILGESVTLPLEFPAGEKV
    NFITWLFNETSLAFIVPHETKSPEIHVTNPKQGKRLNFTQSYSLQLSNLK
    MEDTGSYRAQISTKTSAKLSSYTLRILRQLRNIQVTNHSQLFQNMTCELH
    LTCSVEDADDNVSFRWEALGNTLSSQPNLTVSWDPRISSEQDYTCIAENA
    VSNLSFSVSAQKLCEDVKIQYTDTKMILFMVSGICIVFGFIILLLLVLRK
    RRDSLSLSTQRTQGPAESARNLEYVSVSPTNNTVYASVTHSNRETEIWTP
    RENDTITIYSTINHSKESKPTFSRATALDNVV

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • StrepII and Flag tag at the N-terminus
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SLAMF6
  • Full Name
  • SLAM family member 6
  • Introduction
  • The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
  • Alternative Names
  • SLAMF6; KALI; NTBA; CD352; KALIb; Ly108; NTB-A; SF2000; NK-T-B-antigen; NTBA receptor; activating NK receptor; natural killer-, T- and B-cell antigen; SLAM family member 6

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