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Magic™ Membrane Protein Human SLC22A12 (Solute carrier family 22 member 12) Full Length (CAT#: MPC0769K) Made to Order

Datasheet
This product is a 59.6 kDa Human SLC22A12 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLC22A12
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 59.6 kDa
  • TMD
  • 12
  • Sequence
  • MAFSELLDLVGGLGRFQVLQTMALMVSIMWLCTQSMLENFSAAVPSHRCW
    APLLDNSTAQASILGSLSPEALLAISIPPGPNQRPHQCRRFRQPQWQLLD
    PNATATSWSEADTEPCVDGWVYDRSIFTSTIVAKWNLVCDSHALKPMAQS
    IYLAGILVGAAACGPASDRFGRRLVLTWSYLQMAVMGTAAAFAPAFPVYC
    LFRFLLAFAVAGVMMNTGTLLMEWTAARARPLVMTLNSLGFSFGHGLTAA
    VAYGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGRLDWGLQELW
    RVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLRMPGLRFRT
    CISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLL
    SHLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFT
    CITIYSSELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLV
    YGTVPVLSGLAALLLPETQSLPLPDTIQDVQNQAVKKATHGTLGNSVLKS
    TQF

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SLC22A12
  • Full Name
  • Solute carrier family 22 member 12
  • Introduction
  • The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • RST; OAT4L; URAT1; solute carrier family 22 member 12; organic anion transporter 4-like protein; renal-specific transporter; solute carrier family 22 (organic anion/cation transporter), member 12; solute carrier family 22 (organic anion/urate transporter), member 12; urate anion exchanger 1; urate transporter 1; SLC22A12; Solute carrier family 22 member 12

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