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Magic™ Membrane Protein Human SLC4A10 (Solute carrier family 4 member 10) Full Length (CAT#: MPC0873K) Made to Order

This product is a 125.9 kDa Human SLC4A10 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLC4A10
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 125.9 kDa
  • TMD
  • 12
  • Sequence
  • MEIKDQGAQMEPLLPTRNDEEAVVDRGGTRSILKTHFEKEDLEGHRTLFI
    GVHVPLGGRKSHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDTPSQRVQ
    FILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDG
    GERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQV
    SSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFADIGKKQSEPN
    SMDKNAGQVVSPQSAPACVENKNDVSRENSTVDFSKGLGGQQKGHTSPCG
    MKQRHEKGPPHQQEREVDLHFMKKIPPGAEASNILVGELEFLDRTVVAFV
    RLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVF
    HDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKR
    KIPAVPNGTAAHGEAEPHGGHSGPELQRTGRIFGGLILDIKRKAPYFWSD
    FRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASM
    TGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLW
    TATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEA
    YPINMHNDLELLTQYSCNCVEPHNPSNGTLKEWRESNISASDIIWENLTV
    SECKSLHGEYVGRACGHDHPYVPDVLFWSVILFFSTVTLSATLKQFKTSR
    YFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRG
    WFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGC
    GYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQ
    PKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSL
    KGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWII
    KVSRAAIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDA
    EKEEEQSMLAMEDEGTVQLPLEGHYRDDPSVINISDEMSKTALWRNLLIT
    ADNSKDKESSFPSKSSPS

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SLC4A10
  • Full Name
  • Solute carrier family 4 member 10
  • Introduction
  • This gene belongs to a small family of sodium-coupled bicarbonate transporters (NCBTs) that regulate the intracellular pH of neurons, the secretion of bicarbonate ions across the choroid plexus, and the pH of the brain extracellular fluid. The protein encoded by this gene was initially identified as a sodium-driven chloride bicarbonate exchanger (NCBE) though there is now evidence that its sodium/bicarbonate cotransport activity is independent of any chloride ion countertransport under physiological conditions. This gene is now classified as a member A10 of the SLC4 family of transmembrane solute carriers. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
  • Alternative Names
  • NCBE; NBCn2; sodium-driven chloride bicarbonate exchanger; solute carrier family 4, sodium bicarbonate cotransporter-like, member 10; solute carrier family 4, sodium bicarbonate transporter, member 10; SLC4A10; Solute carrier family 4 member 10

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