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Magic™ Membrane Protein Human SORL1 (Sortilin related receptor 1) Expressed in HEK293 for Antibody Discovery, Partial (82-753aa) (CAT#: MPX0116K)

Datasheet
This product is a 76 kDa Human SORL1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SORL1
  • Protein Length
  • Partial (82-753aa)
  • Protein Class
  • Transporter
  • Molecular Weight
  • 76 kDa
  • TMD
  • 1
  • Sequence
  • SAALQPEPIKVYGQVSLND
    SHNQMVVHWAGEKSNVIVALARDSLALARPKSSDVYVSYDYGKSFKKISD
    KLNFGLGNRSEAVIAQFYHSPADNKRYIFADAYAQYLWITFDFCNTLQGF
    SIPFRAADLLLHSKASNLLLGFDRSHPNKQLWKSDDFGQTWIMIQEHVKS
    FSWGIDPYDKPNTIYIERHEPSGYSTVFRSTDFFQSRENQEVILEEVRDF
    QLRDKYMFATKVVHLLGSEQQSSVQLWVSFGRKPMRAAQFVTRHPINEYY
    IADASEDQVFVCVSHSNNRTNLYISEAEGLKFSLSLENVLYYSPGGAGSD
    TLVRYFANEPFADFHRVEGLQGVYIATLINGSMNEENMRSVITFDKGGTW
    EFLQAPAFTGYGEKINCELSQGCSLHLAQRLSQLLNLQLRRMPILSKESA
    PGLIIATGSVGKNLASKTNVYISSSAGARWREALPGPHYYTWGDHGGIIT
    AIAQGMETNELKYSTNEGETWKTFIFSEKPVFVYGLLTEPGEKSTVFTIF
    GSNKENVHSWLILQVNATDALGVPCTENDYKLWSPSDERGNECLLGHKTV
    FKRRTPHATCFNGEDFDRPVVVSNCSCTREDYECDFGFKMSEDLSLEVCV
    PDPEFSGKSYSPPVPCPVGSTYRRTRGYRKISGDTCSGGDVEARLEGELV
    PCP

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 1 mg/mL in PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • SORL1
  • Full Name
  • Sortilin related receptor 1
  • Introduction
  • This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded preproprotein is proteolytically processed to generate the mature receptor, which likely plays roles in endocytosis and sorting. Mutations in this gene may be associated with Alzheimer's disease.
  • Alternative Names
  • SORL1; LR11; LRP9; SORLA; gp250; SorLA-1; C11orf32; sortilin-related receptor; LDLR relative with 11 ligand-binding repeats; low-density lipoprotein receptor relative with 11 ligand-binding repeats; mosaic protein LR11; sortilin-related receptor, L(DLR class) A repeats containing; sorting protein-related receptor containing LDLR class A repeats; Sortilin related receptor 1

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