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Magic™ Membrane Protein Human TAPT1 (Transmembrane anterior posterior transformation 1) Full Length (CAT#: MPC1366K) Made to Order

Datasheet
This product is a 64.2 kDa Human TAPT1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TAPT1
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • Molecular Weight
  • 64.2 kDa
  • TMD
  • 5
  • Sequence
  • MAGVGDAAAPGEGGGGGVDGPQRDGRGEAEQPGGSGGQGPPPAPQLTETL
    GFYESDRRRERRRGRTELSLLRFLSAELTRGYFLEHNEAKYTERRERVYT
    CLRIPRELEKLMVFGIFLCLDAFLYVFTLLPLRVFLALFRLLTLPCYGLR
    DRRLLQPAQVCDILKGVILVICYFMMHYVDYSMMYHLIRGQSVIKLYIIY
    NMLEVADRLFSSFGQDILDALYWTATEPKERKRAHIGVIPHFFMAVLYVF
    LHAILIMVQATTLNVAFNSHNKSLLTIMMSNNFVEIKGSVFKKFEKNNLF
    QMSNSDIKERFTNYVLLLIVCLRNMEQFSWNPDHLWVLFPDVCMVIASEI
    AVDIVKHAFITKFNDITADVYSEYRASLAFDLVSSRQKNAYTDYSDSVAR
    RMGFIPLPLAVLLIRVVTSSIKVQGILSYACVILFYFGLISLKVLNSIVL
    LGKSCQYVKEAKMEEKLSNPPATCTPGKPSSKSQNKCKPSQGLSTEENLS
    ASITKQPIHQKENIIPLLVTSNSDQFLTTPDGDEKDITQDNSELKHRSSK
    KDLLEIDRFTICGNRID

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • TAPT1
  • Full Name
  • Transmembrane anterior posterior transformation 1
  • Introduction
  • This gene encodes a highly conserved protein that localizes to the centrosome and/or ciliary basal body. Mutations in this gene disrupt Golgi morphology and trafficking and normal primary cilium formation and these mutations are congenitally manifested by severe undermineralization of the intra-uterine skeleton. A mutation in the mouse ortholog of this gene results in homeotic, posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants. In mouse, this gene is thought to function downstream of homeobox C8 to transduce extracellular patterning information during axial skeleton development.
  • Alternative Names
  • TAPT1; CMVFR; OCLSBG; transmembrane anterior posterior transformation protein 1 homolog; cytomegalovirus partial fusion receptor; Transmembrane anterior posterior transformation 1

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