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Magic™ Membrane Protein Human TBC1D20 (TBC1 domain family member 20) Full Length (CAT#: MPC4872K) Made to Order

This product is a made-to-order Human TBC1D20 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TBC1D20
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • TMD
  • 2
  • Sequence
  • MALRSAQGDGPTSGHWDGGAEKADFNAKRKKKVAEIHQALNSDPTDVAAL
    RRMAISEGGLLTDEIRRKVWPKLLNVNANDPPPISGKNLRQMSKDYQQVL
    LDVRRSLRRFPPGMPEEQREGLQEELIDIILLILERNPQLHYYQGYHDIV
    VTFLLVVGERLATSLVEKLSTHHLRDFMDPTMDNTKHILNYLMPIIDQVN
    PELHDFMQSAEVGTIFALSWLITWFGHVLSDFRHVVRLYDFFLACHPLMP
    IYFAAVIVLYREQEVLDCDCDMASVHHLLSQIPQDLPYETLISRAGDLFV
    QFPPSELAREAAAQQQAERTAASTFKDFELASAQQRPDMVLRQRFRGLLR
    PEDRTKDVLTKPRTNRFVKLAVMGLTVALGAAALAVVKSALEWAPKFQLQ
    LFP

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • TBC1D20
  • Full Name
  • TBC1 domain family member 20
  • Introduction
  • This gene encodes a protein that belongs to a family of GTPase activator proteins of Rab-like small GTPases. The encoded protein and its cognate GTPase, Rab1, bind the nonstructural protein 5A (NS5A) of the hepatitis C virus (HCV) to mediate viral replication. Depletion of this protein inhibits replication of the virus and HCV infection. Mutations in this gene are associated with Warburg micro syndrome 4. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • TBC1D20; WARBM4; C20orf140; TBC1 domain family member 20

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