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Magic™ Membrane Protein Human TIGIT (T cell immunoreceptor with Ig and ITIM domains) Expressed in E.coli with 6xHis and SUMO tag at the N-terminus for Antibody Discovery, Partial (22-141aa) (CAT#: MPX4262K)

Datasheet
This product is a 29.1kDa Human TIGIT membrane protein expressed in E.coli. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TIGIT
  • Protein Length
  • Partial (22-141aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 29.1kDa
  • TMD
  • 1
  • Sequence
  • MMTGTIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVAPGPGLGLTLQSLTVNDTGEYFCIYHTYPDGTYTGRIFLEVLESSVAEHGARFQIP

Product Description

  • Expression Systems
  • E.coli
  • Tag
  • 6xHis and SUMO tag at the N-terminus
  • Protein Format
  • Soluble
  • Purity
  • >90% as determined by SDS-PAGE
  • Buffer
  • Tris-based buffer, 50% glycerol

Target

  • Target Protein
  • TIGIT
  • Full Name
  • T cell immunoreceptor with Ig and ITIM domains
  • Introduction
  • This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.
  • Alternative Names
  • TIGIT; VSIG9; VSTM3; WUCAM; T-cell immunoreceptor with Ig and ITIM domains; V-set and immunoglobulin domain containing 9; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain containing 3; V-set and transmembrane domain-containing protein 3; VSIG9, VSTM3; Washington University cell adhesion molecule; T cell immunoreceptor with Ig and ITIM domains

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